Bone repair cells for craniofacial regeneration
نویسندگان
چکیده
منابع مشابه
Bone repair cells for craniofacial regeneration.
Reconstruction of complex craniofacial deformities is a clinical challenge in situations of injury, congenital defects or disease. The use of cell-based therapies represents one of the most advanced methods for enhancing the regenerative response for craniofacial wound healing. Both somatic and stem cells have been adopted in the treatment of complex osseous defects and advances have been made ...
متن کاملAngiogenic and osteogenic potential of bone repair cells for craniofacial regeneration.
There has been increased interest in the therapeutic potential of bone marrow derived cells for tissue engineering applications. Bone repair cells (BRCs) represent a unique cell population generated via an ex vivo, closed-system, automated cell expansion process, to drive the propagation of highly osteogenic and angiogenic cells for bone engineering applications. The aims of this study were (1)...
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Bone regeneration is a complex, well-coordinated physiological process. Large quantities of bone regeneration are often required for craniofacial skeletal reconstruction of large bone defects created by trauma, tumor resection, infection, and skeletal abnormalities. Over the last two decades, a tissue engineering and regeneration approach has been developed as an alternative to conventional sur...
متن کاملTissue engineering scaffolds for the regeneration of craniofacial bone.
Current strategies for skeletal regeneration involve the use of autogenous and allogenic bone grafts that may not always be available or safe to use. One alternative is to develop materials for use as scaffolds for the tissue engineering of bone. We created architecturally nanofibrous scaffolds using the electrospinning technique. These calcium phosphate- based materials are porous, have a larg...
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The osseointegration rate of implants is related to their composition and surface roughness. Implant roughness favors both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate (Ca-P) coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. It has been clearly shown in many publications that Ca-P coating accelerates bone formati...
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ژورنال
عنوان ژورنال: Advanced Drug Delivery Reviews
سال: 2012
ISSN: 0169-409X
DOI: 10.1016/j.addr.2012.03.005